Arsenal returned from their midweek mauling in Milan to surrender 2-0 at Sunderland in the FA Cup and Millwall lost by the same scoreline at home to Bolton Wanderers while the 2 other London clubs struggled to earn replays, with Chelsea coming from a goal down to draw 1-1 at home to Birmingham and Tottenham drawing blanks at minnows Stevenage. In other matches Blackpool came unstuck to 2 early goals at Everton and Norwich had their wings clipped 2-1 at home to Leicester while 2 goals at Crawley Town saw Stoke City through despite the visitors playing most of the match with 10 men, and Liverpool rocked Brighton 6-1 at Anfield thanks to 3 own goals.
In Spain Lionel Messi scored 4 times as Valencia were battered 5-1 at Barcelona while 2 goals for Karim Benzema helped leaders Real Madrid to a 4-0 home win over Racing Santander.
In the Champions League Chelsea lost 3-1 at Napoli while there were 1-0 home wins for Basel and Marseille over Bayern Munich and Inter respectively and Real Madrid drew 1-1 at CSKA Moscow.
City sailed 4-0 past reigning Europa League champions Porto in Manchester to go through 6-1 on aggregate while Stoke were knocked out 1-0 at Valencia and Manchester United lost 2-1 at home to Ajax but progressed to the next round 3-2 on aggregate.